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Immunotoxin Methods and Protocols (Methods in Molecular Biology Vol 166)
عنوان کتاب: Immunotoxin Methods and Protocols (Methods in Molecular Biology Vol 166)
مولف: Waltar A. M.D. Hall (Editor)
ناشر: Empty
زبان: English
سال: 2001
شابک: 9780896037755, 9781592591145, 0896037754
حجم فایل: 3.48 MB
نوع فایل: pdf
تعداد صفحات: 302
Hands-on experts from laboratories around the world describe in step-by-step detail their cutting-edge methods for developing and applying these powerful proteins. The conjugates created by these researchers contain entire monoclonal antibodies, single chain antibody fragments, and cytokines as their carrier ligands. Their toxic portion can include such conventional chemotherapeutics as doxirubicin, such ribosome-inactivating proteins the ricin A chain or saporin, or such bacterial toxins as diphtheria toxin. Also described are a variety of applications that demonstrate the versatility of these agents, including the treatment of primary malignant brain tumors, the generation of selective brain lesions to localize critical functions, and the targeting of the AIDS virus. Authoritative and highly practical, Immunotoxin Methods and Protocols provides today's cancer researchers, neuroscientists, and oncologists with state-of-the-art tools for exploring these powerful biological agents and their rapidly increasing applications.
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